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Resumen del libro
| Publisher Summary 1 |
| These 17 papers, including summaries, examine the latest research on the free radical theory of aging and oxidative biochemistry. Contributors describe the basics, then delineate the role of oxidative stress with different model systems, including retrograde response to oxidative stress and cellular senescence and oxidative stress in filamentous fungus, budding yeast, nematode, drosophila and the mouse. A very interesting article takes the comparative approach to mitochondrial free radical production and calorie restriction, and others describe oxidative stress in disease such as diabetes, cancer, hypertension, cardiac ischemia and cardiovascular disease. The articles on future research topics describe reactive oxygen species and signaling molecules along with other current projects. Includes full references and index. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com) |
| Publisher Summary 2 |
| Human aging is a complex phenomenon. This state-of-the-art book discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed. |
| Publisher Summary 3 |
| This state-of-the-art book discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions. Although the causal relationships have not been established, it is necessary to discuss how free radicals are involved in each situation. In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed. |
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